The EANM and SNMMI practice guideline for lymphoscintigraphy and sentinel node localization in breast cancer

Eur J Nucl Med Mol Imaging. 2013 Dec;40(12):1932-47. doi: 10.1007/s00259-013-2544-2. Epub 2013 Oct 2.


Purpose: The accurate harvesting of a sentinel node in breast cancer includes a sequence of procedures with components from different medical specialities, including nuclear medicine, radiology, surgical oncology and pathology. The aim of this document is to provide general information about sentinel lymph node detection in breast cancer patients.

Methods: The Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the European Association of Nuclear Medicine (EANM) have written and approved these guidelines to promote the use of nuclear medicine procedures with high quality. The final result has been discussed by distinguished experts from the EANM Oncology Committee, the SNMMI and the European Society of Surgical Oncology (ESSO).

Conclusion: The present guidelines for nuclear medicine practitioners offer assistance in optimizing the diagnostic information from the SLN procedure. These guidelines describe protocols currently used routinely, but do not include all existing procedures. They should therefore not be taken as exclusive of other nuclear medicine modalities that can be used to obtain comparable results. It is important to remember that the resources and facilities available for patient care may vary.

Publication types

  • Practice Guideline

MeSH terms

  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / pathology*
  • Health Personnel
  • Humans
  • Image Interpretation, Computer-Assisted
  • Lymphoscintigraphy / methods*
  • Molecular Imaging / methods*
  • Neoadjuvant Therapy
  • Nuclear Medicine / methods*
  • Patient Positioning
  • Quality Control
  • Radiometry
  • Radiopharmaceuticals
  • Sentinel Lymph Node Biopsy / methods*
  • Societies, Scientific*


  • Radiopharmaceuticals