[Infection Rate With Adenivirus 1 to 39 in Infants and Adults]

Immun Infekt. 1985 May;13(3):108-12.
[Article in German]

Abstract

To study the infection rate with adenoviruses (Ad) in infants, sera from 75 infants aged 8 to 26 months were tested for neutralizing antibodies against Ad 1 to 39. Antibodies against Ad 1, 2, 5, and 6 were frequently found, against Ad 7 more rarely, whereas one serum reacted with each Ad 3, 4, 18, 31, and 37 and none with all other types. A significant association of positive reactions against several or all of Ad 1, 2, 5, and 6 was observed in neutralization, but not in hemagglutination inhibition, probably due to a subgenus-specific antibody response. The titer of neutralizing antibodies in human gammaglobulin was determined as an estimate for the prevalence of Ad 1 to 39 in the general population.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoviridae Infections / epidemiology*
  • Adenovirus Infections, Human / epidemiology*
  • Adenovirus Infections, Human / microbiology
  • Adenoviruses, Human / classification
  • Adenoviruses, Human / immunology*
  • Adult
  • Age Factors
  • Antibodies, Viral / analysis*
  • Child, Preschool
  • Germany, West
  • Hemagglutination Inhibition Tests
  • Humans
  • Infant
  • Neutralization Tests
  • Serotyping
  • gamma-Globulins / analysis

Substances

  • Antibodies, Viral
  • gamma-Globulins