Hematol Oncol Clin North Am. 2013 Oct;27(5):957-74. doi: 10.1016/j.hoc.2013.07.002. Epub 2013 Aug 26.


This article presents an overview of the current literature about the biology, pathology, and the clinical management of leiomyosarcoma. In addition, the article emphasizes and discusses the current systemic treatment options available for patients with leiomyosarcoma, which range from cytotoxic chemotherapy to target therapies. Particular leiomyosarcoma subtypes, such as uterine leiomyosarcoma and inferior vena cava leiomyosarcoma, are discussed separately.

Keywords: Chemotherapy; Leiomyosarcoma; Prognostic factors; Targeted therapy; Uterine leiomyosarcoma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Leiomyosarcoma / diagnosis*
  • Leiomyosarcoma / epidemiology
  • Leiomyosarcoma / etiology
  • Leiomyosarcoma / therapy*