Malignant soft tissue tumors in children

Orthop Clin North Am. 2013 Oct;44(4):657-67. doi: 10.1016/j.ocl.2013.07.002.


Soft tissue masses are frequently seen in children. Although most are benign or reactive, soft tissue sarcomas (STS)-both rhabdomyosarcoma (most common) and non-rhabdo STS, do occur in the extremities. Appropriate evaluation of extremity soft tissue tumors often includes a biopsy as the clinical and imaging features may not be enough to establish a definitive diagnosis. Much needs to be done for improving the treatment of these rare but often devastating sarcomas. Given the small numbers of these cases seen at various centers, collaborative efforts should be made to further our understanding and improve the management of these challenging cases.

Keywords: Extremity; Lump; Pediatric; Sarcoma; Soft tissue mass; Soft tissue tumor.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Child
  • Cytogenetics
  • Humans
  • Immunohistochemistry
  • Neoplasm Staging
  • Sarcoma / diagnosis
  • Sarcoma / genetics
  • Sarcoma / therapy*
  • Soft Tissue Neoplasms / diagnosis
  • Soft Tissue Neoplasms / genetics
  • Soft Tissue Neoplasms / therapy*