Detection of boronic acids through excited-state intramolecular proton-transfer fluorescence

Org Lett. 2013 Oct 18;15(20):5382-5. doi: 10.1021/ol402714k. Epub 2013 Oct 7.


Boronic acids are versatile reagents for the chemical synthesis of organic molecules. They and other boron-containing compounds can be detected readily by the interruption of the excited-state intramolecular proton transfer (ESIPT) of 10-hydroxybenzo[h]quinolone. This method is highly sensitive and selective, and useful for monitoring synthetic reactions and detecting boron-containing compounds on a solid support.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boronic Acids / analysis*
  • Fluorescence*
  • Molecular Structure
  • Protons*
  • Quinolones / chemistry*


  • Boronic Acids
  • Protons
  • Quinolones