Similar articles

• Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.

  Ohno M, Hiraoka Y, Lichtenthaler SF, Nishi K, Saijo S, Matsuoka T, Tomimoto H, Araki W, Takahashi R, Kita T, Kimura T, Nishi E. Ohno M, et al. Neurobiol Aging. 2014 Jan;35(1):213-22. doi: 10.1016/j.neurobiolaging.2013.07.014. Epub 2013 Aug 15. Neurobiol Aging. 2014. PMID: 23954170
• ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function.

  Suh J, Choi SH, Romano DM, Gannon MA, Lesinski AN, Kim DY, Tanzi RE. Suh J, et al. Neuron. 2013 Oct 16;80(2):385-401. doi: 10.1016/j.neuron.2013.08.035. Epub 2013 Sep 19. Neuron. 2013. PMID: 24055016 Free PMC article.
• BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease.

  Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, Wang J, Kumaravel G, Taveras AG, Moore Arnold H, Rhodes KJ. Scannevin RH, et al. Neuropharmacology. 2016 Apr;103:57-68. doi: 10.1016/j.neuropharm.2015.12.006. Epub 2015 Dec 12. Neuropharmacology. 2016. PMID: 26690893
• Effects of altered RTN3 expression on BACE1 activity and Alzheimer's neuritic plaques.

  Sharoar MG, Yan R. Sharoar MG, et al. Rev Neurosci. 2017 Feb 1;28(2):145-154. doi: 10.1515/revneuro-2016-0054. Rev Neurosci. 2017. PMID: 27883331 Review.
• Alzheimer's disease drug development based on Computer-Aided Drug Design.

  Zeng H, Wu X. Zeng H, et al. Eur J Med Chem. 2016 Oct 4;121:851-863. doi: 10.1016/j.ejmech.2015.08.039. Epub 2015 Sep 3. Eur J Med Chem. 2016. PMID: 26415837 Review.