Geminiviruses: masters at redirecting and reprogramming plant processes

Nat Rev Microbiol. 2013 Nov;11(11):777-88. doi: 10.1038/nrmicro3117. Epub 2013 Oct 8.


The family Geminiviridae is one of the largest and most important families of plant viruses. The small, single-stranded DNA genomes of geminiviruses encode 5-7 proteins that redirect host machineries and processes to establish a productive infection. These interactions reprogramme plant cell cycle and transcriptional controls, inhibit cell death pathways, interfere with cell signalling and protein turnover, and suppress defence pathways. This Review describes our current knowledge of how geminiviruses interact with their plant hosts and the functional consequences of these interactions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Geminiviridae / physiology*
  • Gene Expression Regulation, Viral / physiology
  • Genome, Viral
  • Host-Pathogen Interactions
  • Plant Diseases / virology
  • Viral Proteins / genetics
  • Viral Proteins / metabolism


  • Viral Proteins