Cellular aging: symmetry evades senescence

James B Moseley

doi:10.1016/j.cub.2013.08.013

Cellular aging: symmetry evades senescence

Curr Biol. 2013 Oct 7;23(19):R871-3. doi: 10.1016/j.cub.2013.08.013.

Author

James B Moseley¹

Affiliation

¹ Department of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA. Electronic address: james.b.moseley@dartmouth.edu.

Abstract

Cellular aging programs typically rely on the asymmetric shape and growth pattern of cells. A new study shows that symmetric fission yeast cells escape classic signs of aging until they encounter environmental stress.

Publication types

Comment

MeSH terms

Adenosine Triphosphatases / genetics*
Asymmetric Cell Division / physiology*
Cellular Senescence / physiology*
Heat-Shock Proteins / genetics*
Schizosaccharomyces / physiology*
Stress, Physiological / physiology*

Substances

Heat-Shock Proteins
Adenosine Triphosphatases
HSP104 protein, S pombe

Grant support

R01 GM099774/GM/NIGMS NIH HHS/United States