Multiagent chemotherapy for metastatic adenocarcinoma of the seminal vesicle

Anticancer Drugs. 2014 Jan;25(1):115-9. doi: 10.1097/CAD.0000000000000030.

Abstract

Adenocarcinoma of the seminal vesicle is a rare condition, with fewer than 60 cases described in the literature. Most reports highlight the histopathological characteristics of the tumor; however, the role of chemotherapy, especially in the metastatic setting, is poorly described. In this paper, we describe a patient with metastatic disease, who sustained a response to modified FOLFOX6 as first-line therapy. This platinum-based combination therapy seems effective in this scenario and may provide an opportunity for extended survival and relief of symptoms.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / secondary
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Fluorouracil / therapeutic use
  • Genital Neoplasms, Male / drug therapy*
  • Genital Neoplasms, Male / pathology
  • Humans
  • Leucovorin / therapeutic use
  • Male
  • Organoplatinum Compounds / therapeutic use
  • Palliative Care
  • Platinum / administration & dosage
  • Platinum / therapeutic use
  • Seminal Vesicles / pathology*

Substances

  • Organoplatinum Compounds
  • Platinum
  • Leucovorin
  • Fluorouracil

Supplementary concepts

  • Folfox protocol