Photoreceptor cell-specific localization of S-antigen in retina

Curr Eye Res. 1985 Jun;4(6):703-6. doi: 10.3109/02713688509017665.


Retinal S-antigen has been found to be localized in a specific photoreceptor cell population of squirrel (Tamias striatus) and rhesus monkey retina. In these cone-rich retinas S-antigen seems only to be present in the rods. Differential immunofluorescent staining of the photoreceptor cells was accomplished by using monospecific rabbit-anti bovine S-antigen antiserum, which exhibits very limited species specificity. In view of its co-localization with rhodopsin in rods and considering data from literature, we suggest that S-antigen is a major component of the phototransduction system in these cells.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Antigens / analysis*
  • Arrestin
  • Epitopes / analysis
  • Fluorescent Antibody Technique
  • Macaca mulatta
  • Photoreceptor Cells / immunology*
  • Rats
  • Rats, Inbred Strains
  • Retina / immunology*
  • Rhodopsin / metabolism
  • Sciuridae


  • Antigens
  • Arrestin
  • Epitopes
  • Rhodopsin