orthAgogue: an agile tool for the rapid prediction of orthology relations

Bioinformatics. 2014 Mar 1;30(5):734-6. doi: 10.1093/bioinformatics/btt582. Epub 2013 Oct 9.


Motivation: The comparison of genes and gene products across species depends on high-quality tools to determine the relationships between gene or protein sequences from various species. Although some excellent applications are available and widely used, their performance leaves room for improvement.

Results: We developed orthAgogue: a multithreaded C application for high-speed estimation of homology relations in massive datasets, operated via a flexible and easy command-line interface.

Availability: The orthAgogue software is distributed under the GNU license. The source code and binaries compiled for Linux are available at https://code.google.com/p/orthagogue/.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Sequence Alignment
  • Sequence Homology*
  • Software*