Singular expression of olfactory receptor genes

Cell. 2013 Oct 10;155(2):274-7. doi: 10.1016/j.cell.2013.09.032.


Understanding the mechanisms of monogenic and monoallelic transcription of the large repertoire of olfactory receptor genes represents a challenging task. A picture is now emerging in which odorant receptor choice and stabilization involve an escape from silencing followed by the activation of an unconventional feedback loop.

Publication types

  • Review

MeSH terms

  • Animals
  • Feedback
  • Gene Expression Regulation*
  • Humans
  • Olfactory Receptor Neurons / metabolism*
  • Receptors, Odorant / genetics*
  • Receptors, Odorant / metabolism
  • Stochastic Processes
  • Transcription, Genetic


  • Receptors, Odorant