Emergence of Acinetobacter baumannii international clone II in Brazil: reflection of a global expansion

Infect Genet Evol. 2013 Dec:20:378-80. doi: 10.1016/j.meegid.2013.09.028. Epub 2013 Oct 10.

Abstract

The aim of this study was to investigate the occurrence of carbapenem-resistant Acinetobacter baumannii international clones (IC) in Curitiba, Brazil, using multilocus sequence typing and trilocus PCR-based typing schemes. IC2 was the first emerging clone. This IC was detected in an isolate from 2003 of a PFGE type spread in at least two hospitals since 1999. Subsequently, IC2 waned while IC1 and clonal complex 15/104 prevailed. This is the first description of IC2 in Brazil and Latin America.

Keywords: Acinetobacter baumannii; International clone; Molecular epidemiology; Multilocus sequence typing; Trilocus PCR-based typing.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter Infections / drug therapy*
  • Acinetobacter Infections / epidemiology*
  • Acinetobacter Infections / microbiology
  • Acinetobacter baumannii / drug effects*
  • Acinetobacter baumannii / genetics
  • Acinetobacter baumannii / isolation & purification
  • Bacterial Typing Techniques
  • Brazil / epidemiology
  • Carbapenems / therapeutic use*
  • Humans
  • Multilocus Sequence Typing
  • beta-Lactam Resistance / genetics*

Substances

  • Carbapenems