Clinical care in craniofacial microsomia: a review of current management recommendations and opportunities to advance research

Am J Med Genet C Semin Med Genet. 2013 Nov;163C(4):271-82. doi: 10.1002/ajmg.c.31373. Epub 2013 Oct 16.


Craniofacial microsomia (CFM) is a complex condition associated with microtia, mandibular hypoplasia, and preauricular tags. It is the second most common congenital facial condition treated in many craniofacial centers and requires longitudinal multidisciplinary patient care. The purpose of this article is to summarize current recommendations for clinical management and discuss opportunities to advance clinical research in CFM.

Keywords: craniofacial microsomia; facial asymmetry; hemifacial microsomia; mandibular hypoplasia; microtia.

Publication types

  • Review

MeSH terms

  • Congenital Abnormalities / genetics
  • Congenital Abnormalities / pathology
  • Congenital Abnormalities / therapy*
  • Congenital Microtia
  • Ear / abnormalities*
  • Ear / pathology
  • Facial Asymmetry / genetics
  • Facial Asymmetry / pathology
  • Facial Asymmetry / therapy*
  • Goldenhar Syndrome / genetics
  • Goldenhar Syndrome / pathology
  • Goldenhar Syndrome / therapy*
  • Humans