Single-channel currents of an intercellular junction

Nature. 1985 Sep 26-Oct 2;317(6035):331-5. doi: 10.1038/317331a0.

Abstract

We have used a double whole-cell patch-clamp system to make the first quantitative recordings of the single-channel current from an intercellular junction, presumably a gap junction. The junctional channel has various conductance states and discriminates poorly between cations and anions. It seems to change slowly from one conductance state to another.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Intercellular Junctions / physiology*
  • Ion Channels / physiology*
  • Ions
  • Kinetics
  • Lacrimal Apparatus / physiology
  • Membrane Potentials
  • Models, Biological
  • Rats

Substances

  • Ion Channels
  • Ions