Abstract
Blood CXCR5⁺ CD4⁺ T cells share phenotypic and functional similarities with T follicular helper cells. Studies by He et al. (2013) and Locci et al. (2013) in this issue of Immunity provide insight into their ontogeny and functionally distinct subsets.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Animals
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Antibodies / immunology*
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Antibodies, Neutralizing / biosynthesis*
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HIV Antibodies / biosynthesis*
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HIV Infections / immunology*
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HIV-1 / immunology*
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Humans
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Immunologic Memory*
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Programmed Cell Death 1 Receptor / immunology*
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Receptors, CXCR / immunology*
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Receptors, CXCR5 / immunology*
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T-Lymphocytes, Helper-Inducer / immunology*
Substances
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ACKR3 protein, human
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Antibodies
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Antibodies, Neutralizing
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CXCR5 protein, human
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HIV Antibodies
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PDCD1 protein, human
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Programmed Cell Death 1 Receptor
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Receptors, CXCR
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Receptors, CXCR5