A "big data" view of the tumor "immunome"

Immunity. 2013 Oct 17;39(4):631-2. doi: 10.1016/j.immuni.2013.10.002.

Abstract

Tumors are complex masses containing not just neoplastic cells but also stromal cells, neovasculature, and a gamut of immune cells. In this issue, Bindea et al. (2013) identify a surprising new "immune landscape" associated with prolonged disease-free survival.

Publication types

  • Comment

MeSH terms

  • Animals
  • B-Lymphocytes / immunology*
  • Carcinoma / immunology*
  • Chemokine CXCL13 / immunology*
  • Colorectal Neoplasms / immunology*
  • Humans
  • Interleukins / immunology*
  • Neoplasm Recurrence, Local / immunology*
  • T-Lymphocytes, Helper-Inducer / immunology*

Substances

  • CXCL13 protein, human
  • Chemokine CXCL13
  • Interleukins
  • interleukin-21