[Prognosis assessment of alcoholic liver disease: how and why?]

Presse Med. 2014 Feb;43(2):124-34. doi: 10.1016/j.lpm.2013.04.016. Epub 2013 Oct 17.
[Article in French]


Alcoholic liver disease (ALD) causes more than 5000 deaths per year in France. Most of those deaths could be prevented by an early diagnosis, which would give the patients the opportunity to modify their alcohol consumption while liver lesions are still reversible. Hepatic histology is the main parameter that predicts morbidity and mortality in patients with ALD. Non-invasive methods such as biomarker tests (e.g. FibroTest(®) or FibroMetre A(®)) or hepatic elastography (FibroScan(®)) may allow diagnosing alcohol-induced liver lesion without systematic biopsy. Despite promising preliminary results, those methods are not validated yet in ALD. A validation of non-invasive methods for ALD could allow a large screening of the severe forms of this pathology.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Biomarkers
  • Female
  • Humans
  • Liver / pathology*
  • Liver Cirrhosis / diagnosis*
  • Liver Diseases, Alcoholic / diagnosis*
  • Male
  • Prognosis


  • Biomarkers