Improvement of motor function and decreased need for postnatal shunting in children who had undergone intrauterine myelomeningocele repair

Arq Neuropsiquiatr. 2013 Sep;71(9A):604-8. doi: 10.1590/0004-282X20130104.

Abstract

Objective: To compare neuromotor development between patients who did and those who did not undergo intrauterine myelomeningocele repair.

Methods: Children with myelomeningocele aged between 3.5 and 6 years who did undergo intrauterine repair (Group A, n=6) or not (Group B; n=7) were assessed for neuromotor development at both anatomical and functional levels, need for orthoses, and cognitive function.

Results: Intrauterine myelomeningocele repair significantly improved motor function. The functional level was higher than the anatomical level by 2 or more spinal segments in all children in Group A and 2 children in Group B, with a significant statistical difference between groups (p<0.05). Five children in Group A and one in Group B were community ambulators.

Conclusion: Despite the small sample, it was observed that an improvement of motor function and decreased need for postnatal shunting in the 6 children who had undergone intrauterine myelomeningocele repair.

MeSH terms

  • Child
  • Child, Preschool
  • Cognition Disorders / etiology
  • Cognition Disorders / prevention & control*
  • Cognition Disorders / rehabilitation
  • Developmental Disabilities / etiology
  • Developmental Disabilities / prevention & control*
  • Developmental Disabilities / rehabilitation
  • Disability Evaluation
  • Disabled Children
  • Fetal Diseases / surgery*
  • Fetoscopy*
  • Humans
  • Meningomyelocele / complications
  • Meningomyelocele / surgery*
  • Motor Skills Disorders / etiology
  • Motor Skills Disorders / prevention & control*
  • Motor Skills Disorders / rehabilitation
  • Prenatal Diagnosis
  • Treatment Outcome