Abstract
A HIV-positive child presented with acute onset of right hemiplegia, facial palsy and dysphasia 4 weeks after commencing highly active antiretroviral therapy. Magnetic resonance imaging confirmed a left-sided cerebral infarct. Cerebrospinal fluid polymerase chain reaction was positive for varicella zoster virus. This is the first reported pediatric case of varicella zoster virus-related immune reconstitution inflammatory syndrome involving the central nervous system.
MeSH terms
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Antiretroviral Therapy, Highly Active / adverse effects*
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Cerebral Infarction / chemically induced
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Cerebral Infarction / etiology*
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Cerebral Infarction / virology
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Child
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Encephalitis, Varicella Zoster / cerebrospinal fluid
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Encephalitis, Varicella Zoster / virology*
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Female
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HIV Infections / cerebrospinal fluid
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HIV Infections / drug therapy*
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HIV Infections / virology
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Humans
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Immune Reconstitution Inflammatory Syndrome / cerebrospinal fluid
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Immune Reconstitution Inflammatory Syndrome / virology*