Orthokeratology for slowing myopic progression in a pair of identical twins

Cont Lens Anterior Eye. 2014 Apr;37(2):116-9. doi: 10.1016/j.clae.2013.09.007. Epub 2013 Oct 19.


Purpose: To compare the axial length elongation and change in refractive errors in a pair of identical twins wearing orthokeratology (ortho-k) and single vision lenses (SVLs), respectively.

Case report: Identical Twin A and B, who were 8 years of age, with the same amount of near activities, were assigned to wear ortho-k and SVLs randomly and they were monitored for two years for myopic progression. Twin A and B were assigned to wear ortho-k and SVLs, respectively. Myopic progression was evaluated by the change in axial length and in refractive errors. A faster axial length elongation was observed in each eye of Twin B during the two-year study period. The overall change in axial length was 0.52mm (OD) and 0.70 (OS) in Twin A and 0.77mm (OD) and 0.82mm (OS) in Twin B. In terms of cycloplegic refractive errors (SER), one month after ceasing lens wear (after completion of the two-year study), the increase (from baseline) were 11% (OD) and 48% (OS) in Twin A and 87% (OD) and 67% (OS) in Twin B.

Conclusions: Ortho-k is more effective in controlling myopic progression in terms of axial elongation than wearing SVLs in this pair of identical twins.

Keywords: Axial length; Myopic control; Orthokeratology; Refractive errors; Twins.

Publication types

  • Case Reports
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contact Lenses*
  • Disease Progression
  • Female
  • Humans
  • Male
  • Myopia / diagnosis*
  • Myopia / therapy*
  • Orthokeratologic Procedures / instrumentation*
  • Orthokeratologic Procedures / methods*
  • Treatment Outcome
  • Twins, Monozygotic*