How to decide intervention thresholds based on FRAX in central south Chinese postmenopausal women

Zhimin Zhang; Yangna Ou; Zhifeng Sheng; Eryuan Liao

doi:10.1007/s12020-013-0076-y

How to decide intervention thresholds based on FRAX in central south Chinese postmenopausal women

Endocrine. 2014 Mar;45(2):195-7. doi: 10.1007/s12020-013-0076-y. Epub 2013 Oct 22.

Authors

Zhimin Zhang¹, Yangna Ou, Zhifeng Sheng, Eryuan Liao

Affiliation

¹ Institute of Metabolism and Endocrinology, The Second Xiang-Ya Hospital, Central South University, 139 Renmin-Zhong Rd, Changsha, 410011, Hunan, People's Republic of China.

Abstract

The FRAX tool has been used to determine possible thresholds for therapeutic intervention; however, there are no FRAX-based intervention thresholds available for China, we proposed that the 10-year probability of major osteoporotic fracture and hip fracture of about 4.0 and 1.3%, respectively, may be acceptable intervention thresholds for central south Chinese postmenopausal women.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Asian People*
Bone Density / physiology*
China / epidemiology
Early Medical Intervention*
Female
Femur Neck / physiology*
Hip Fractures / epidemiology
Hip Fractures / ethnology
Humans
Middle Aged
Models, Statistical*
Osteoporosis, Postmenopausal / epidemiology*
Osteoporosis, Postmenopausal / ethnology
Osteoporosis, Postmenopausal / physiopathology
Osteoporotic Fractures / epidemiology*
Osteoporotic Fractures / ethnology
Osteoporotic Fractures / physiopathology
Risk Assessment / methods
Risk Factors
Time Factors
World Health Organization