Study on antibacterial effect of medlar and hawthorn compound extract in vitro

Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):567-73. doi: 10.4314/ajtcam.v10i3.27. eCollection 2013.


This paper evaluated the antibacterial effect of medlar and hawthorn compound extract in vitro. Water extract method and ethanol extraction method was adopted to prepare the compound extracts, and disc diffusion method and improved test tube doubling dilution method were used to conduct the antibacterial test on the two common pathogenic bacteria, Staphylococcus aureus and Klebsiella pneumonia, in vitro. The results showed that medlar and hawthorn compound extract was moderately sensitive to Staphylococcus aureus, while its inhibiting effect on Klebsiella pneumoniae was particularly significant, moreover, the antibacterial effect of ethanol extract was better than water extract. Medlar and hawthorn compounds had good antibacterial effect on the two pathogenic bacteria.

Keywords: Antibacterial activity; Killing curve; Medlar and hawthorn compound; content measuring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Crataegus*
  • Klebsiella pneumoniae / drug effects*
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology*
  • Rosaceae*
  • Staphylococcus aureus / drug effects*


  • Anti-Bacterial Agents
  • Plant Extracts