[Tuberculosis and HIV co-infection: clinical trial under the coordination of the Institut Pasteur in Cambodia]

Med Sci (Paris). 2013 Oct;29(10):908-11. doi: 10.1051/medsci/20132910020. Epub 2013 Oct 18.
[Article in French]

Abstract

Tuberculosis is a major cause of death among adults infected by HIV. The CAMELIA (ANRS 1295/CIPRA KH001) randomized clinical trial aimed to determine the optimal timing of ARV initiation after tuberculosis treatment onset to reduce mortality. Here, we describe the trial implementation in five hospitals in Cambodia under the coordination of the Institut Pasteur in Cambodia, its conduct, the challenges and public health benefits in Cambodia and beyond.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Academies and Institutes / organization & administration*
  • Adult
  • Anti-Retroviral Agents / administration & dosage
  • Antitubercular Agents / administration & dosage
  • Cambodia
  • Coinfection
  • HIV Infections / complications
  • HIV Infections / epidemiology
  • HIV Infections / therapy*
  • HIV-1 / physiology
  • Humans
  • International Cooperation*
  • Randomized Controlled Trials as Topic*
  • Tuberculosis / complications
  • Tuberculosis / epidemiology
  • Tuberculosis / therapy*

Substances

  • Anti-Retroviral Agents
  • Antitubercular Agents