Malignant potential of endometrial stromal tumor with limited infiltration: a case report

Int J Surg Pathol. 2014 Sep;22(6):559-63. doi: 10.1177/1066896913506934. Epub 2013 Oct 23.

Abstract

Endometrial stromal tumors (ESTs) with limited infiltration were first proposed by Dionigi et al.(1) However, the prognostic significance of these tumors is unclear. We report a case of a 60-year-old woman who presented with a prolapsed uterine corpus and then underwent laparoscopic-assisted vaginal hysterectomy. A very small EST was incidentally found. The tumor manifested focal irregularity and finger-like permeation into the adjacent myometrium not exceeding 3 mm but exceeding 3 in number, features intermediate between a low-grade endometrial stromal sarcoma and an endometrial stromal nodule. By definition, we rendered a descriptive diagnosis of "endometrial stromal tumor with limited infiltration." A subsequent staging operation confirmed metastasis and, hence, a malignant potential.

Keywords: endometrial stromal nodule; endometrial stromal tumor with limited infiltration; low-grade endometrial stromal sarcoma; malignant potential.

Publication types

  • Case Reports

MeSH terms

  • Endometrial Neoplasms / pathology*
  • Endometrial Stromal Tumors / pathology*
  • Female
  • Humans
  • Middle Aged