Identification and characterization of eleven novel human gamma-papillomavirus isolates from healthy skin, found at low frequency in a normal population

PLoS One. 2013 Oct 14;8(10):e77116. doi: 10.1371/journal.pone.0077116. eCollection 2013.


Eleven novel human papillomavirus (HPV) types were isolated and characterized from healthy individuals in China. HPV163 belongs to the γ-1 species, HPV 164 and HPV 168 fit in the γ-8 species, HPV 165 and KC5 belongs to the γ-12 species, HPV 168 is closely allied with the γ-4 species, HPV 169 is closely related to the γ-11 species, and HPV 170 is related to the γ-12 species. In addition, HPV 161, HPV 162, and HPV 166 may form a new HPV species of the γ-PV genus. The prevalence of these HPV types in the normal population is low.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Coinfection / virology
  • Genome, Viral / genetics
  • Humans
  • Molecular Sequence Data
  • Open Reading Frames / genetics
  • Papillomaviridae / genetics*
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / virology
  • Phylogeny
  • Prevalence
  • Skin / virology*

Associated data

  • GENBANK/JX413102
  • GENBANK/JX413104
  • GENBANK/JX413105
  • GENBANK/JX413106
  • GENBANK/JX413107
  • GENBANK/JX413108
  • GENBANK/JX413109
  • GENBANK/JX444072
  • GENBANK/JX444073
  • GENBANK/KC862317
  • GENBANK/KC862318

Grants and funding

This work was supported by the grants from the 973 project (201202014), the National Natural Sciences Foundation of China (30930102), the Beijing Natural Science Foundation (7100001), and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20110001110037). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.