A fluorescent probe for the biological signaling molecule H2S based on a specific H2S trap group

Chem Commun (Camb). 2013 Dec 14;49(96):11305-7. doi: 10.1039/c3cc46932h. Epub 2013 Oct 24.

Abstract

A fluorescent turn-on probe for H2S was exploited based on a H2S-induced substitution-cyclization cascade reaction towards the bis-electrophilic centers of a new H2S trap group 2-(iodomethyl)benzoate.

MeSH terms

  • Animals
  • Benzoates / chemistry
  • COS Cells
  • Chlorocebus aethiops
  • Fluorescent Dyes / chemistry*
  • Hydrogen Sulfide / analysis*
  • Microscopy, Fluorescence
  • Optical Imaging*
  • Spectrometry, Fluorescence

Substances

  • Benzoates
  • Fluorescent Dyes
  • Hydrogen Sulfide