Intravenous immune serum globulin in immune thrombocytopenia: clinical results and biochemical evaluation

Vox Sang. 1985;49 Suppl 1:44-50. doi: 10.1111/j.1423-0410.1985.tb01143.x.

Abstract

Intravenous gamma-globulin of the pH 4-treated Swiss Red Cross (SRC) preparation is an effective therapy for acute and chronic immune thrombocytopenia (ITP) of childhood and chronic ITP in adults. Patients who may respond satisfactorily to treatment include those without detectable immune complexes and those with poor response to pretreatment. Results are especially good in children, half of whom with chronic conditions are able to discontinue therapy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Platelets / immunology
  • Cell Aggregation
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunization, Passive*
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Infant
  • Infusions, Parenteral
  • Middle Aged
  • Phagocytosis
  • Plasmapheresis
  • Platelet Count
  • Thrombocytopenia / immunology
  • Thrombocytopenia / therapy*
  • gamma-Globulins / administration & dosage*

Substances

  • Immunoglobulin G
  • Immunoglobulin M
  • gamma-Globulins