A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species

Extremophiles. 2014 Jan;18(1):51-60. doi: 10.1007/s00792-013-0591-z. Epub 2013 Oct 27.

Abstract

A newly isolated single-tailed fusiform virus, Sulfolobus tengchongensis spindle-shaped virus STSV2, from Hamazui, China, is characterised. It contains a double-stranded modified DNA genome of 76,107 bp and is enveloped by a lipid membrane structure. Virions exhibit a single coat protein that forms oligomers when isolated. STSV2 is related to the single-tailed fusiform virus STSV1 and, more distantly, to the two-tailed bicaudavirus ATV. The virus can be stably cultured over long periods in laboratory strains of Sulfolobus and no evidence was found for cell lysis under different stress conditions. Therefore, it constitutes an excellent model virus for archaeal virus-host studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Archaeal Viruses / genetics*
  • Archaeal Viruses / metabolism
  • Archaeal Viruses / ultrastructure
  • Base Sequence
  • Capsid Proteins / chemistry
  • Capsid Proteins / genetics*
  • Capsid Proteins / metabolism
  • Genome, Viral
  • Molecular Sequence Data
  • Sulfolobus / virology*

Substances

  • Capsid Proteins