Interrupted development of dentition in children receiving bone marrow transplantation for acute lymphocytic Leukemia: a case series

Spec Care Dentist. 2013 Nov-Dec;33(6):308-11. doi: 10.1111/j.1754-4505.2012.00315.x. Epub 2012 Dec 11.

Abstract

This case series depicts dental anomalies that may develop in children who have undergone bone marrow transplantation (BMT) for acute lymphoblastic leukemia (ALL). The most common finding in these patients was root stunting; other abnormalities included microdontia, hypodontia, taurodontia, caries, enamel pearls, and pulpal calcification. Recognition of these adverse effects of BMT on odontogenesis, as demonstrated on panoramic radiograph images, will allow healthcare providers to explain to parents and patients the possible dental outcomes associated with BMT and to optimize their dental health regimen.

Keywords: acute lymphocytic leukemia; bone marrow transplantation; dentition; hypodontia; panoramic radiograph.

Publication types

  • Case Reports

MeSH terms

  • Bone Marrow Transplantation / adverse effects*
  • Child
  • Child, Preschool
  • Dentition*
  • Female
  • Humans
  • Infant
  • Male
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / surgery*