Raised C-reactive protein levels in serum from smokers

Clin Chim Acta. 1985 Nov 29;153(1):9-13. doi: 10.1016/0009-8981(85)90133-0.


Investigation of a possible quantitative relationship between the extent of tissue injury due to inhalation of tobacco smoke and changes in concentrations of a number of acute phase proteins were studied in smokers. Smokers showed an acute phase response as indicated by significantly raised serum C-reactive protein levels. Significant lowering of serum albumin levels was also observed in smokers. Serum levels of alpha 1-antitrypsin, alpha 1-antichymotrypsin, alpha 1-acid glycoprotein, transferrin and haptoglobin did not show any significant changes due to inhalation of tobacco smoke. Although the C-reactive protein test is non-specific, evidence for elevated levels of C-reactive protein indicates the presence of tissue inflammation.

MeSH terms

  • Acute-Phase Proteins
  • Adult
  • Blood Proteins / analysis
  • C-Reactive Protein / analysis*
  • Female
  • Humans
  • Inflammation / blood
  • Male
  • Smoking*


  • Acute-Phase Proteins
  • Blood Proteins
  • C-Reactive Protein