Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Feb;19(2):265-71.
doi: 10.1038/mp.2013.120. Epub 2013 Oct 29.

Playing Super Mario Induces Structural Brain Plasticity: Gray Matter Changes Resulting From Training With a Commercial Video Game

Affiliations

Playing Super Mario Induces Structural Brain Plasticity: Gray Matter Changes Resulting From Training With a Commercial Video Game

S Kühn et al. Mol Psychiatry. .

Erratum in

  • Mol Psychiatry. 2014 Feb;19(2):272

Abstract

Video gaming is a highly pervasive activity, providing a multitude of complex cognitive and motor demands. Gaming can be seen as an intense training of several skills. Associated cerebral structural plasticity induced has not been investigated so far. Comparing a control with a video gaming training group that was trained for 2 months for at least 30 min per day with a platformer game, we found significant gray matter (GM) increase in right hippocampal formation (HC), right dorsolateral prefrontal cortex (DLPFC) and bilateral cerebellum in the training group. The HC increase correlated with changes from egocentric to allocentric navigation strategy. GM increases in HC and DLPFC correlated with participants' desire for video gaming, evidence suggesting a predictive role of desire in volume change. Video game training augments GM in brain areas crucial for spatial navigation, strategic planning, working memory and motor performance going along with evidence for behavioral changes of navigation strategy. The presented video game training could therefore be used to counteract known risk factors for mental disease such as smaller hippocampus and prefrontal cortex volume in, for example, post-traumatic stress disorder, schizophrenia and neurodegenerative disease.

Similar articles

See all similar articles

Cited by 68 articles

See all "Cited by" articles

References

    1. Prog Brain Res. 1990;83:301-12 - PubMed
    1. Neurobiol Aging. 2004 Mar;25(3):377-96 - PubMed
    1. Arch Neurol. 2003 Jul;60(7):989-94 - PubMed
    1. Front Hum Neurosci. 2012 May 17;6:142 - PubMed
    1. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1181-8 - PubMed

LinkOut - more resources

Feedback