Mode of action and effects of 5-azacytidine and of its derivatives in eukaryotic cells

Pharmacol Ther. 1985;28(2):227-35. doi: 10.1016/0163-7258(85)90012-9.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antimetabolites, Antineoplastic / pharmacology
  • Antimetabolites, Antineoplastic / therapeutic use
  • Azacitidine / analogs & derivatives
  • Azacitidine / pharmacology*
  • Azacitidine / therapeutic use
  • Cells / drug effects*
  • Cytidine / pharmacology
  • Drug Resistance
  • Enzyme Activation / drug effects
  • Eukaryotic Cells / drug effects*
  • Humans
  • Leukemia, Experimental / drug therapy
  • Liver Regeneration / drug effects
  • Uridine Kinase / metabolism

Substances

  • Antimetabolites, Antineoplastic
  • 5,6-dihydro-5-azacytidine
  • Cytidine
  • fazarabine
  • Uridine Kinase
  • Azacitidine
  • pseudoisocytidine