The Terminator Mouse: Salvation for Primary Cell Culture

Kidney Int. 2013 Nov;84(5):866-8. doi: 10.1038/ki.2013.288.

Abstract

The Terminator had to come back from the future already several times in an effort to bring salvation to mankind. In the present issue of Kidney International, Guo et al. brought us a novel transgenic mouse model: the terminator mouse. This highly elegant mouse may facilitate significantly the derivation of primary cultures of a specific cell type from a tissue containing multiple cell populations.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Lineage*
  • Heparin-binding EGF-like Growth Factor
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Kidney Tubules, Proximal / metabolism*
  • Podocytes / metabolism*

Substances

  • Hbegf protein, mouse
  • Heparin-binding EGF-like Growth Factor
  • Intercellular Signaling Peptides and Proteins