The disappearance of human chorionic gonadotropin from plasma and urine following induced abortion. Disappearance of HCG after induced abortion

Acta Obstet Gynecol Scand. 1985;64(7):547-52. doi: 10.3109/00016348509156360.


In 28 females, daily measurement of the HCG concentration in urine and in 15 of them daily measurement of the beta-HCG concentration in plasma was carried out during the first 2 weeks following first-trimester induced abortion by vacuum aspiration. Plasma beta-HCG concentration fell according to a multi-exponential curve with a half-life of 0.63 days in the first 2 days following induced abortion, and of 3.85 days in the subsequent 14 days. The disappearance of HCG from urine is exponential, with a half-life value of 1.3 days. A urine pregnancy test with a sensitivity of 1 IU/ml wil nearly always be negative in the course of 2 weeks after abortion. A positive test 4 weeks after abortion indicates an incomplete abortion or persistent trophoblast.

MeSH terms

  • Abortion, Induced*
  • Adolescent
  • Adult
  • Chorionic Gonadotropin / metabolism*
  • Chorionic Gonadotropin, beta Subunit, Human
  • Female
  • Half-Life
  • Humans
  • Peptide Fragments / metabolism*
  • Pregnancy
  • Pregnancy Trimester, First


  • Chorionic Gonadotropin
  • Chorionic Gonadotropin, beta Subunit, Human
  • Peptide Fragments