Safety assessment of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics

Int J Toxicol. Sep-Oct 2013;32(5 Suppl):56S-64S. doi: 10.1177/1091581813504596.

Abstract

The Cosmetic Ingredient Review Expert Panel assessed the safety of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics, finding that these ingredients are safe in cosmetic formulations in the present practices of use and concentration. Both ingredients are lanolin substitutes and are reported to function in cosmetics as skin-conditioning agents--emollients. The Panel reviewed available animal and clinical data in making its determination of safety.

Keywords: bis-diglyceryl polyacyladipate; cosmetics; safety.

Publication types

  • Review

MeSH terms

  • Adipates / chemistry
  • Adipates / toxicity*
  • Animals
  • Consumer Product Safety
  • Cosmetics
  • Emollients / chemistry
  • Emollients / toxicity*
  • Humans
  • Mutagenicity Tests
  • Skin / drug effects

Substances

  • Adipates
  • Cosmetics
  • Emollients