PRC1 marks the difference in plant PcG repression

Mol Plant. 2014 Mar;7(3):459-71. doi: 10.1093/mp/sst150. Epub 2013 Oct 31.

Abstract

From mammals to plants, the Polycomb Group (PcG) machinery plays a crucial role in maintaining the repression of genes that are not required in a specific differentiation status. However, the mechanism by which PcG machinery mediates gene repression is still largely unknown in plants. Compared to animals, few PcG proteins have been identified in plants, not only because just some of these proteins are clearly conserved to their animal counterparts, but also because some PcG functions are carried out by plant-specific proteins, most of them as yet uncharacterized. For a long time, the apparent lack of Polycomb Repressive Complex (PRC)1 components in plants was interpreted according to the idea that plants, as sessile organisms, do not need a long-term repression, as they must be able to respond rapidly to environmental signals; however, some PRC1 components have been recently identified, indicating that this may not be the case. Furthermore, new data regarding the recruitment of PcG complexes and maintenance of PcG repression in plants have revealed important differences to what has been reported so far. This review highlights recent progress in plant PcG function, focusing on the role of the putative PRC1 components.

Keywords: H2A monoubiquitination; PRC1; Polycomb Group; chromatin compaction.; epigenetic regulation; gene repression.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism
  • Epigenesis, Genetic / genetics*
  • Glucosyltransferases / genetics
  • Glucosyltransferases / metabolism
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Polycomb-Group Proteins / genetics
  • Polycomb-Group Proteins / metabolism*
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism*

Substances

  • Arabidopsis Proteins
  • Plant Proteins
  • Polycomb-Group Proteins
  • Repressor Proteins
  • Glucosyltransferases
  • PRC1 protein, Arabidopsis