Gibberellins and DELLAs: central nodes in growth regulatory networks

Trends Plant Sci. 2014 Apr;19(4):231-9. doi: 10.1016/j.tplants.2013.10.001. Epub 2013 Oct 30.

Abstract

Gibberellins (GAs) are growth-promoting phytohormones that were crucial in breeding improved semi-dwarf varieties during the green revolution. However, the molecular basis for GA-induced growth stimulation is poorly understood. In this review, we use light-regulated hypocotyl elongation as a case study, combined with a meta-analysis of available transcriptome data, to discuss the role of GAs as central nodes in networks connecting environmental inputs to growth. These networks are highly tissue-specific, with dynamic and rapid regulation that mostly occurs at the protein level, directly affecting the activity and transcription of effectors. New systems biology approaches addressing the role of GAs in growth should take these properties into account, combining tissue-specific interactomics, transcriptomics and modeling, to provide essential knowledge to fuel a second green revolution.

Keywords: DELLAs; cell expansion; cell proliferation; gibberellins; growth; systems biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arabidopsis Proteins / metabolism
  • Gibberellins / metabolism*
  • Models, Biological
  • Plant Proteins / metabolism*

Substances

  • Arabidopsis Proteins
  • GAI protein, Arabidopsis
  • Gibberellins
  • Plant Proteins