Glucose tolerance test and insulin levels in children with transfusion-dependent thalassaemia

Ann Trop Paediatr. 1985 Dec;5(4):215-8. doi: 10.1080/02724936.1985.11748396.

Abstract

Blood glucose and serum immunoreactive insulin levels were measured following an oral glucose load in 20 unrelated children with multiple transfused thalassaemia. Results suggest that even though overt diabetes and glucose intolerance are uncommon before the age of 13 years, the presence of insulin resistance is evident, especially in those who have been splenectomized.

MeSH terms

  • Adolescent
  • Blood Glucose / analysis
  • Blood Transfusion*
  • Child
  • Child, Preschool
  • Female
  • Glucose Tolerance Test*
  • Humans
  • Infant
  • Insulin / blood*
  • Insulin / immunology
  • Male
  • Splenectomy
  • Thalassemia / blood*
  • Thalassemia / therapy

Substances

  • Blood Glucose
  • Insulin