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. 2013 Nov;15(11):1265-7.
doi: 10.1038/ncb2878.

Hedgehog Threads to Spread

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Hedgehog Threads to Spread

James Briscoe et al. Nat Cell Biol. .

Abstract

In vivo time-lapse imaging and functional tests bring fresh evidence that the morphogen Hedgehog is conveyed to target cells via long filopodia extensions, dubbed cytonemes. This study provides the tools and conceptual framework to understand how cytonemes form and carry morphogens.

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