Hedgehog threads to spread

Nat Cell Biol. 2013 Nov;15(11):1265-7. doi: 10.1038/ncb2878.


In vivo time-lapse imaging and functional tests bring fresh evidence that the morphogen Hedgehog is conveyed to target cells via long filopodia extensions, dubbed cytonemes. This study provides the tools and conceptual framework to understand how cytonemes form and carry morphogens.

Publication types

  • Comment

MeSH terms

  • Animals
  • Drosophila Proteins / metabolism*
  • Hedgehog Proteins / metabolism*


  • Drosophila Proteins
  • Hedgehog Proteins
  • hh protein, Drosophila