An efficient convergent synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2 (1) by Pd(0)-catalyzed coupling between the boronate ester (upper fragment) and the enol triflate (A-ring fragment) is described. This article is part of a Special Issue entitled '16th Vitamin D Workshop'.
Keywords: 1α,25-Dihydroxyvitamin D(2) d(9); Isotopic labelling; Vitamin D(2) analogues synthesis.
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