Abstract
We describe a child with acute post-streptococcal glomerulonephritis (APSGN), who developed a very low plasma high-density lipoprotein cholesterol (α-lipoprotein) in association with transient but massive proteinuria. The hypoalphalipoproteinaemia resolved spontaneously concomitant with the remission in proteinuria and the patient had a complete clinical recovery. Urinary loss of apolipoprotein A1 may have contributed to the hypoalphalipoproteinaemia. To our knowledge, this has not been reported previously in APSGN.
MeSH terms
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Acute Disease
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Anti-Bacterial Agents / therapeutic use
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Child, Preschool
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Cholesterol, HDL / metabolism*
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Cholesterol, HDL / urine
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Follow-Up Studies
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Glomerulonephritis / etiology*
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Glomerulonephritis / physiopathology
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Glomerulonephritis / therapy
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Humans
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Male
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Proteinuria / etiology
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Proteinuria / physiopathology
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Rare Diseases
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Risk Assessment
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Severity of Illness Index
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Streptococcal Infections / complications
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Streptococcal Infections / diagnosis*
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Streptococcal Infections / drug therapy
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Cholesterol, HDL