Reduced level of 25-hydroxyvitamin D in chronic/relapsing Alopecia Areata

Dermatoendocrinol. 2013 Apr 1;5(2):271-3. doi: 10.4161/derm.24411. Epub 2013 Jan 1.


Current observations link vitamin D deficiency to many autoimmune diseases. There are limited data on vitamin D in Alopecia Areata, an autoimmune disease which in our experience shows seasonality in most of its remitting-relapsing forms. Our results demonstrate the presence of insufficiency of 25-hydroxyvitamin D (25OH-D) in many patients with various clinical forms, correlated with the expected increase of the values of Parathyroid Hormone (PTH). This could suggest the possible clinical use of vitamin D in the management of this frustrating disease.

Keywords: Alopecia Areata; autoimmunity; seasonality; vitamin D.