The comprehensive management of pregnant women with major mood disorders: a case study involving phenelzine, lithium, and quetiapine

Arch Womens Ment Health. 2014 Feb;17(1):73-5. doi: 10.1007/s00737-013-0386-3. Epub 2013 Nov 8.


Pregnancy in women with severe mental illness (SMI) often bring added dimensions of complexity; considering that this group of women are choosing to have children at increasing rates, more highly complex cases will require management. A 31-year-old primigravida with a diagnosis of bipolar affective disorder was treated with an antidepressant, mood stabiliser and antipsychotic. This case discusses preconception counselling, pregnancy and labour management that resulted in the delivery of a 4,200 g baby at 39 weeks by emergency caesarian section. This case highlights the collaborative approach to care that is needed in this group of women and the need for increasing awareness and knowledge in health professionals. It follows the management from preconception through to the postpartum period.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antidepressive Agents / adverse effects
  • Antidepressive Agents / therapeutic use*
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Bipolar Disorder / diagnosis
  • Bipolar Disorder / drug therapy*
  • Bipolar Disorder / psychology
  • Cesarean Section
  • Dibenzothiazepines / adverse effects
  • Dibenzothiazepines / therapeutic use*
  • Female
  • Humans
  • Infant, Newborn
  • Lithium / therapeutic use*
  • Phenelzine / adverse effects
  • Phenelzine / therapeutic use*
  • Preconception Care
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / psychology
  • Pregnancy Outcome
  • Prenatal Exposure Delayed Effects
  • Quetiapine Fumarate
  • Treatment Outcome


  • Antidepressive Agents
  • Antipsychotic Agents
  • Dibenzothiazepines
  • Quetiapine Fumarate
  • Lithium
  • Phenelzine