Modeling human liver biology using stem cell-derived hepatocytes

Int J Mol Sci. 2013 Nov 6;14(11):22011-21. doi: 10.3390/ijms141122011.

Abstract

Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cell Differentiation
  • Embryonic Stem Cells / cytology
  • Embryonic Stem Cells / metabolism*
  • Hepatocytes / metabolism*
  • Hepatocytes / pathology
  • Humans
  • Liver / cytology
  • Liver / metabolism
  • Liver / physiopathology*
  • Liver Diseases / drug therapy
  • Liver Diseases / metabolism
  • Liver Diseases / physiopathology*
  • Liver Diseases / virology