A patient with steroids and antihistaminic drug allergy and newly occurred chronic urticaria angioedema: what about omalizumab?

Hum Exp Toxicol. 2014 Aug;33(8):882-5. doi: 10.1177/0960327113510539. Epub 2013 Nov 7.

Abstract

In this case report, successful use of omalizumab in the treatment of chronic urticarial and angioedema in a 24-year-old female patient with an allergic reaction history to almost every drug including steroids and antihistamines was presented. She also had allergy against a large number of foods, which were confirmed by oral provocation, specific Immunoglobulin E and allergy skin test.

Keywords: Allergy; drug; omalizumab.

Publication types

  • Case Reports

MeSH terms

  • Angioedema / chemically induced*
  • Angioedema / diagnosis
  • Angioedema / drug therapy*
  • Angioedema / immunology
  • Anti-Allergic Agents / therapeutic use*
  • Antibodies, Anti-Idiotypic / therapeutic use*
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Biomarkers / blood
  • Drug Hypersensitivity / diagnosis
  • Drug Hypersensitivity / drug therapy*
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / immunology
  • Female
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / immunology
  • Histamine Antagonists / adverse effects*
  • Humans
  • Immunoglobulin E / blood
  • Omalizumab
  • Skin Tests
  • Steroids / adverse effects*
  • Treatment Outcome
  • Urticaria / chemically induced*
  • Urticaria / diagnosis
  • Urticaria / immunology
  • Young Adult

Substances

  • Anti-Allergic Agents
  • Antibodies, Anti-Idiotypic
  • Antibodies, Monoclonal, Humanized
  • Biomarkers
  • Histamine Antagonists
  • Steroids
  • Omalizumab
  • Immunoglobulin E