The ability to perform a sit-to-stand (STS) motion is important for ambulatory adults to function independently and maintain daily activities. Roughly 6% of community-dwelling older adults experience significant difficulties with STS, a major risk factor for institutionalization. While mechanical STS assistance can help address this problem, full dependence on STS assistance provided by devices such as lift chairs can lead to atrophy of the leg muscles. We investigated the mechanics of assisted STS motion in order to better understand how load-sharing STS mechanisms may facilitate STS motions while still requiring activation of the leg muscles. Experiments were conducted with 17 nondisabled older adults performing unassisted and assisted STS rises with grab bar, arm, seat, and waist assistance. Each mode of rise was evaluated based on a subject questionnaire and key biomechanical metrics relating to stability, knee effort reduction, and rise trajectory. Results show that the seat- and waist-assist modes provide statistically significant improvements in stability metrics and reductions in required knee torques over unassisted rises and bar assistance. The assists most preferred by the subjects were the seat and bar assists. Overall, our results favor a seat-assisted STS modality for nonclinical applications and indicate further testing of this modality with a clinical population.