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Multicenter Study
. 2013 Nov-Dec;26(6):720-7.
doi: 10.3122/jabfm.2013.06.120260.

Human papillomavirus (HPV) testing for normal cervical cytology in low-risk women aged 30-65 years by family physicians

Maria Syl D de la Cruz  1 , Alisa P Young, Mack T Ruffin 4th
Affiliations
Multicenter Study

Human papillomavirus (HPV) testing for normal cervical cytology in low-risk women aged 30-65 years by family physicians

Maria Syl D de la Cruz et al. J Am Board Fam Med. 2013 Nov-Dec.

Abstract

Purpose: The purpose of this study was to assess ordering of human papillomavirus (HPV) testing for normal cervical cytology among low-risk women aged 30 to 65 years.

Methods: Audits of 833 cytology request forms for low-risk women completing a Papanicolaou smear, from January 2008 to April 2011, from 5 Michigan family medicine clinics determined HPV orders completed by the clinician performing the Papanicolaou smear. Multivariate logistic regression models examined differences in HPV test ordering by patient age at Papanicolaou test, provider status and sex, and clinic across sites. A Poisson regression model analyzed the annual number of HPV test orders over time.

Results: Cytology requests were completed by 622 faculty (75%), 169 residents/fellows (20%), and 42 nurse practitioner/physician assistants (NP/PAs) (5%). HPV testing for any cytology result was ordered on 324 request forms (39%) by residents/fellows (48%), faculty (38%), and NP/PAs (10%). Female providers were twice as likely as men to order HPV testing for any cytology result across all clinics and provider statuses (P < .001). There were significant differences in HPV test ordering among clinics. Between 2008 and 2011 annual cytology requests increased 46%, including HPV testing for any cytology result after adjusting for faculty provider sex.

Conclusion: HPV test ordering when cytology is collected varied by clinic and provider status and sex. HPV co-testing for any cytology result remains modest, but is increasing over time in these clinics.

Keywords: Diagnostic Use; Human Papilloma Virus DNA Probes; Mass Screening; Vaginal Smears.

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Conflict of interest statement

Conflicts of interest The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Age of patient at time of cervical cytology collection by clinics and provider status with 95% confidence intervals
Figure 2
Figure 2
HPV order by Provider Status (p< 0.001)
Figure 3
Figure 3
HPV order by Provider Status and Provider Gender (p< 0.001)
Figure 4
Figure 4
HPV order by Provider Gender and Clinic A and B (resident and faculty clinics), p<0.001
Figure 5
Figure 5
HPV order by Provider Gender and Clinics C, D, and E (faculty-only clinics), p<0.001
Figure 6
Figure 6
Percent of Pap Smear with orders for HPV testing for “All Results” over time by faculty gender.
See this image and copyright information in PMC

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