Normal variation of P300 from auditory stimuli

Electroencephalogr Clin Neurophysiol. 1986 May;65(3):236-40. doi: 10.1016/0168-5597(86)90059-6.

Abstract

The P300 (P3) event-related potential was obtained from 100 undergraduates with a 2-tone auditory discrimination task (20% targets) and replicated trial block procedure. Normal variation for P3 amplitude and latency was assessed with frequency distributions and descriptive statistics for the midline electrode placements. P3 latency and amplitude were negatively correlated, most strongly at the Pz electrode site. No significant effects between trial block replications, subject gender, or reported alcohol consumption on either amplitude or latency were found.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acoustic Stimulation*
  • Adult
  • Alcoholism / genetics
  • Discrimination, Psychological / drug effects
  • Discrimination, Psychological / physiology
  • Electroencephalography
  • Electrooculography
  • Ethanol / pharmacology
  • Evoked Potentials, Auditory* / drug effects
  • Female
  • Humans
  • Male
  • Reaction Time / drug effects
  • Reaction Time / physiology
  • Sex Factors

Substances

  • Ethanol