Abstract
We report molecular evidence of Tula hantavirus as an etiologic agent of pulmonary-renal syndrome in an immunocompromised patient. Acute hantavirus infection was confirmed by using serologic and molecular methods. Sequencing revealed Tula virus genome RNA in the patient's blood. This case shows that Tula virus can cause serious disease in humans.
Keywords:
Tula virus; hantavirus; hantavirus pulmonary syndrome; hemorrhagic fever with renal syndrome; immunocompromised host; viruses.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Antibodies, Viral / immunology
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Czech Republic
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Genome, Viral
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Glomerulonephritis / diagnosis*
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Hantavirus Infections / diagnosis*
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Hemorrhage / diagnosis*
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Humans
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Immunocompromised Host*
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Lung Diseases / diagnosis*
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Male
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Molecular Sequence Data
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Orthohantavirus / classification*
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Orthohantavirus / genetics*
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Orthohantavirus / immunology
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Phylogeny
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RNA, Viral
Substances
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Antibodies, Viral
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RNA, Viral
Supplementary concepts
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Rapidly progressive glomerulonephritis with pulmonary hemorrhage
Associated data
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GENBANK/KC494908
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GENBANK/KC522413